A Deep Dive into Collagen's Amino Acid Profile

A Deep Dive into Collagen's Amino Acid Profile

Collagen, the most abundant protein in our bodies, is often lauded for its skin-enhancing, joint-supporting, and gut-healing properties. But what makes collagen so unique and effective? The answer lies in its amino acid profile. Amino acids, often referred to as the "building blocks of life," come together to form proteins, including collagen. In this article, we'll delve deep into the amino acids present in collagen and their specific roles and benefits.

1. Glycine

Making up about one-third of collagen's amino acid composition, glycine is a non-essential amino acid that plays a critical role in collagen's structure.


  • DNA and RNA synthesis: Glycine aids in the construction of our genetic material.
  • Detoxification: It supports the liver in detoxification processes.
  • Neurotransmitter function: Glycine acts as an inhibitory neurotransmitter in the central nervous system.

2. Proline

Proline, another major component of collagen, contributes to collagen's unique triple helix structure.


  • Joint and cartilage support: Proline helps maintain and repair joints and cartilage.
  • Wound healing: It plays a role in the body's wound-healing processes.

3. Hydroxyproline

Derived from proline through a vitamin C-dependent reaction, hydroxyproline is vital for collagen stability.


  • Collagen stability: Hydroxyproline helps form the tight triple helix structure of collagen, ensuring its stability and strength.

4. Arginine

Arginine, a semi-essential amino acid, plays various roles in the body, including in collagen synthesis.


  • Nitric oxide production: Arginine is a precursor for nitric oxide, which helps in vasodilation and improved blood flow.
  • Cell division and wound healing: It supports various cellular functions.

5. Glutamine

Present in collagen, glutamine is an amino acid that offers numerous health benefits.


  • Gut health: Glutamine supports the cells of the gut lining, aiding in maintaining a healthy gut barrier.
  • Immune system support: It plays a role in immune cell function.

6. Lysine

Lysine, an essential amino acid, contributes to collagen's structure and function.


  • Calcium absorption: Lysine helps the body absorb calcium and decreases its excretion.
  • Collagen cross-linking: It aids in the formation of collagen's complex structure.


The power of collagen lies in its rich and unique amino acid profile. These amino acids come together to provide the myriad benefits that collagen offers, from skin health to joint support. When considering collagen supplements, it's essential to choose a high-quality product that provides a comprehensive amino acid profile. SANA Amsterdam, with its commitment to superior quality, ensures that you receive the full spectrum of amino acids, harnessing collagen's complete range of benefits for your health and well-being.

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